Dr. Megan Wasson, D.O.

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Endometriosis Focus

Endometriosis Is the Primary Clinical Focus

Endometriosis is the stated center of Dr. Wasson's clinical and research work. Mayo Clinic's official biography lists minimally invasive procedures for advanced and extra-pelvic endometriosis as the primary clinical interest, with specific mention of obliterated cul de sac, large and small intestine, urinary tract, and diaphragm and thoracic cavity involvement. Uterine and ovarian preservation for patients with endometriosis is also listed as a focus, as is fertility optimization.

Dr. Wasson holds a fellowship from the AAGL in Minimally Invasive Gynecologic Surgery and an ABOG focused-practice designation in MIGS (minimally invasive gynecologic surgery). It is worth noting that MIGS fellowship training is broader than endometriosis-specific fellowship training; however, Dr. Wasson's published research, conference presentations, and documented surgical case history reflect a sustained and specific focus on endometriosis, including rare and atypical presentations.

Dr. Wasson is listed on Nancy's Nook and trained under Javier Magrina, a surgeon widely recognized in the endo excision community for his work on complex cases. Dr. Wasson has co-published with Magrina on nerve-sparing surgical technique.

Multidisciplinary Approach

Integrated Team at Mayo Clinic Arizona

Dr. Wasson operates within a structured multidisciplinary team at Mayo Clinic Arizona. For surgical cases involving the bowel or colon, a colorectal surgery team is available. Cases involving the urinary tract include urology coordination, including ureteral stent placement when indicated. Thoracic or diaphragmatic involvement is managed in collaboration with cardiothoracic surgery, and patient accounts document thoracoscopy performed during endo surgery for thoracic and diaphragmatic cases.

On the diagnostic and pre-surgical side, Mayo Clinic Arizona has a dedicated radiology team with specialist experience in detecting endometriosis on imaging. Advanced ultrasound and MRI findings are reviewed at multidisciplinary board meetings with the gynecology team prior to surgery. Dr. Wasson has noted publicly that this collaborative radiology process is central to surgical planning and helps reduce the likelihood of incomplete treatment or the need for repeat procedures.

For patients who do not proceed directly to surgery, the practice describes a care pathway that includes access to interventional radiology, gastroenterology, pelvic floor physical therapy, pain psychology, fertility specialists, and genetic counselors depending on individual symptoms. Dr. Wasson has co-authored a published call for multidisciplinary approaches to endometriosis management in the peer-reviewed literature.

Diagnosis Methods

Advanced Imaging Before Surgery, with Explicit Acknowledgment of Standard Imaging Limits

Dr. Wasson uses advanced ultrasound and MRI as standard pre-surgical tools for patients with symptoms of deep infiltrating endometriosis. The radiology team at Mayo Clinic Arizona includes specialists in endo detection on imaging, and their findings are reviewed collaboratively with the gynecology team before any surgery is planned.

Critically, Dr. Wasson has publicly acknowledged that standard imaging frequently misses endometriosis. In a 2026 Instagram post, Dr. Wasson described using a "slide sign" during ultrasound, a technique that assesses how the rectum moves in relation to the uterus, as a supplementary indicator when standard imaging appears normal. Multiple patient accounts describe having MRIs that were read as "negative" by outside providers, with Mayo Clinic's radiology team subsequently identifying endometriosis on the same imaging.

Definitive diagnosis of endometriosis requires surgery. Dr. Wasson has stated that going into the operating room without pre-surgical imaging and planning is not the standard approach at this practice; imaging is used as a roadmap so the surgical team is not surprised by the extent of disease intraoperatively. Tissue removed during surgery is examined under the microscope to confirm the presence or absence of endometriosis.

Educational Presence

Active Researcher, Educator, and International Speaker

Dr. Wasson has over 70 peer-reviewed publications and has delivered more than 200 invited lectures. Research output is heavily concentrated in endometriosis, including published case reports and studies on endo in rare anatomical locations: the spleen, Morrison's Pouch, the pericardium, and presentations including large bowel obstruction. Additional published work covers multidisciplinary management of endometriosis, concurrent adenomyosis and endometriosis, intraoperative detection techniques, nerve-sparing surgical approaches, and advanced preoperative imaging.

Dr. Wasson serves on multiple committees at AAGL and FIGO, including the Endometriosis Special Interest Group at AAGL (since 2014) and as Chair of the Minimal Access Surgery Committee at FIGO (since 2022). Dr. Wasson served as Stream Advisor for the FIGO Cape Town 2025 Scientific Programme and has presented at ACOG, AAGL, SGS, and other major gynecologic surgery conferences. In 2025, Dr. Wasson presented on identifying and excising endometriosis at the ACOG Annual Meeting, with a stated focus on helping clinicians recognize atypical endo presentations that do not match the classic "powder burn" description taught in residency training.

Dr. Wasson holds a professor title at Mayo Clinic College of Medicine and Science and is actively involved in training medical students, residents, and fellows. The practice has a formal surgical fellowship program focused on complex benign gynecology and pelvic pain. Dr. Wasson has stated publicly that expanding the number of trained endo surgeons is a priority, citing the gap between the prevalence of endometriosis and the number of providers equipped to treat it.

Dr. Wasson maintains personal social media accounts on Instagram (@meganwassondo) and TikTok (@drmeganwasson) with endo-focused content, and has a professional Facebook presence. Mayo Clinic has produced multiple patient-education videos featuring Dr. Wasson as the expert. Dr. Wasson appeared on the Endo Battery podcast in July 2025, covering endometriosis at every life stage from adolescence through menopause, and was interviewed by Contemporary OB/GYN at the 2025 ACOG Annual Meeting.

Post-Surgical Care

Personal Follow-Up Documented; Hormonal Approach Addresses Estrogen Nuance

Patient accounts describe post-operative appointments directly with Dr. Wasson, including review of surgical findings and photos. One patient specifically noted seeing Dr. Wasson personally at a post-op appointment to discuss what was found during surgery. Another account describes being visited by Dr. Wasson and the full surgical team during a two-day hospital stay following a complex case requiring chest tube management.

No public information was found on standard follow-up timing, the duration of ongoing post-surgical care, or the specific post-operative protocol used for all patients. Patients should ask directly about these specifics when consulting.

On hormonal management, Dr. Wasson has stated publicly that estrogen is not the enemy and that the goal is to work with the body rather than suppress it entirely. This reflects a more nuanced view than simply prescribing hormonal suppression post-surgery as a default. The Endo Battery podcast appearance in July 2025 included discussion of hormone therapy after endo surgery, HRT in the context of surgical menopause, and the limits of hormonal suppression as a treatment approach.

Philosophy and Fit

Quality of Life as the Treatment Standard; Shared Decision-Making as the Framework

Dr. Wasson has stated publicly that treatment decisions should be guided by patient-reported symptoms and their effect on quality of life, not by imaging findings alone. In a 2025 interview, Dr. Wasson noted that even deep infiltrating endometriosis visible on imaging does not automatically require surgical intervention if the patient is not experiencing symptoms that affect daily functioning. Conversely, for patients who are symptomatic, the stated approach is aggressive and thorough excision, described in the same interview as treating the disease similarly to a malignancy in terms of the surgical standard applied, even though endometriosis is benign.

Dr. Wasson lists shared decision-making as a core part of clinical practice. Patient accounts consistently describe feeling that their care plan was developed collaboratively and that they were not rushed or pressured. The practice's Instagram post describing the care pathway explicitly notes that patients who prefer to see a senior surgeon for the initial consultation rather than a fellow can request this, though they should expect longer wait times as a result.

Dr. Wasson has been explicit in public statements that period pain severe enough to affect daily life is not normal and that the widespread underdiagnosis of endometriosis is a systemic problem, not a patient problem. This framing appears across multiple public appearances and is reflected in the patient accounts on file, where many describe being validated for the first time after years of dismissal.

This practice is based at Mayo Clinic Arizona and sees patients both in person and via telehealth. No referral is required to book an appointment.